Arch. med. vet.  vol.48 no.3; Abstract: S0301-732X2016000300010
Revistas Electrónicas UACh
Web Sistema de Bibliotecas UACh
Formulario de Contacto Revistas Electrónicas UACh (OFF)
Revistas Electrónicas UACh - Archivos de medicina veterinaria
vol.48 no.3Ease of handling, physiological response, skin lesions and meat quality in pigs transported in two truck typesFrequency and antimicrobial behaviour of thermophilic Campylobacter species isolated from Ecuadorian backyard chickens  author indexsubject indexsearch form
Inicio revistaalphabetic serial listing  

Archivos de medicina veterinaria
Print ISSN 0301-732X

  How to cite this article
  Add to favorites article
  Send to E-mail


DORNER, CA, RICK, MC and JUDY, CE. Tiludronate infusion in horses previously submitted to bone scintigraphy. Arch. med. vet., 2016, vol.48, no.3, p.305-310. ISSN 0301-732X.

This study was performed to evaluate the systemic short-term effects of tiludronate intravenous infusion on serum biochemical variables when administered as one single-dose in horses that undergo bone scintigraphy within 24 to 36 hours prior to treatment. Thirty-eight horses were enrolled in the study. Fifteen horses received a dose of technetium (0.3 mCi/kg), MDP (20 mg; medronate) and another fifteen horses received technetium (0.3 mCi/kg), MDP (20 mg), and furosemide (1 mg/kg). Then, 24 to 36 hours after the bone scintigraphy, eight horses were selected and received tiludronate (500 mg in 5L of 0.9% NaCl). Blood samples were collected 15 minutes prior, 24 and 48 hours after the treatment and a chemistry panel was assayed on the day of collection. Serum chemistry values were not significantly different between horses receiving tiludronate and those in both control groups. Additionally, one horse showed mild transient signs of colic recorded as pacing and stretching in the stall after 3 hours the injection of the tiludronic acid. The results suggest that tiludronate can be administered safely as one single dose in horses having undergone recent bone scintigraphy without additional complications or detrimental effect other than those previously described for the drug.

Keywords: horse; bisphosphonates; tiludronate; bone scintigraphy.

        · abstract in spanish     · text in english     · pdf in english

© 2020 • Facultad de Ciencias Veterinarias, Universidad Austral de Chile
Teléfono/Fax: 56 63 221459 • Casilla 567 • Campus Isla Teja S/N • Valdivia • Chile